The uses of hematopoietic stem cell transplantation to restore the production of blood cells in cancer treatment
Hematopoietic stem cells (HSCs) are a limited group of all blood cell types. A study was performed on the spleen of mice undergoing bone marrow transplantation to determine the potential colonization of red blood cells. This bone marrow transplant has been leading in treating malignant...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Book Section |
| Language: | English |
| Published: |
Penerbit UTHM
2022
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| Subjects: | |
| Online Access: | http://eprints.uthm.edu.my/7531/1/8.pdf http://eprints.uthm.edu.my/7531/ |
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| Summary: | Hematopoietic stem cells
(HSCs) are a limited group of all blood
cell types. A study was performed on
the spleen of mice undergoing bone
marrow transplantation to determine
the potential colonization of red blood
cells. This bone marrow transplant has
been leading in treating malignant
diseases. High-dose chemotherapy
with hematopoietic stem cells has
been commonly used in the diagnosis
of haematologic allegiances. This is a
clinical trial of autologous and
allogeneic transplants which takes the
latest developments in blood
progenitor cells into consideration.
Prior to transplantation, patients
underwent intensive myeloablative
chemotherapy with a "rescue" stem
cell. Autologous HSCT was performed
using hematopoietic stem cells of the
patient's own, pre-transplantation
removed and after myeloablation re�injected. This century has produced a
range of approaches and innovations
that have been used including modern
mobilization approaches and the in�vivo production of blood progenitor
cells, the use of core cord blood as
alternative cell source, and molecular
techniques that could include other
forms of purifying tumor cells from
potential autologous lists. |
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