The effect of channa stratus (ikan haruan) extract on post lower segment caesarian section (lscs) women

• Main Author: Kadir, Azidah Abdul
• Format: Monograph
• Language: English
• Published: Pusat Pengajian Kesihatan 2015
• Subjects: RA440-440.87 Study and teaching. Research; RG Gynecology and obstetrics
• Online Access: http://eprints.usm.my/59971/1/PROF%20MADYA%20DR%20AZIAH%20ABDUL%20KARIM%20-%20e.pdf; http://eprints.usm.my/59971/

Channa striatus or its local name Haruan, is a fresh water fish consumed for decades as a remedy to promote wound healing by women during postpartum period. The objectives were to compare post-operative pain score; wound healing, safety profile, anteroposterior (AP) measurement of the uterus, pulsatility index (PI), resistive index (Rl) of uterine artery and superficial skin wound artery between Channa striatus and placebo groups following six weeks of Lower Segment Caesarean Section (LSCS) delivery. This is a randomized, double blind, placebo-controlled study, done in post Lower Segment Caesarean Section (LSCS) women. Subjects were randomized into either Channa striatus or placebo group with daily dosage of 500mg of Channa striatus extract or 500mg maitodextrin respectively for six weeks post-operation. The women were assessed on Post-operative pain score, Wound Evaluation Scale (WES), Visual Analogue Scale (VAS), Patient's Satisfaction Score (PSS), anteroposterior (AP) measurement of the uterus in longitudinal and oblique transverse planes, pulsatility index (PI), resistive index (Rl) of uterine artery and superficial skin wound artery at baseline (day 3), two weeks, four weeks and six weeks post-operatively. The safety profile (RFT, LFT and FBC) were assessed at baseline and six weeks post-operatively.Seventy six subjects were successfully randomised into this study with 38 in Channa striatus group and 38 in placebo group. There were no significant difference detected in terms of post-operative pain (p=0.814), WES (p=0.160), pulsatility index (PI), resistive index (Rl) of uterine artery and superficial skin wound artery between Channa striatus and placebo group. However, (VAS) and (PSS), AP measurement of uterus on longitudinal plane and oblique transverse plane in Channa striatus group was significantly better compared to placebo group. Safety profile showed no significant difference between both groups. In conclusion, the consumption of 500mg of Channa striatus extract daily showed marked differences in cosmetic appearance, patient’s satisfaction towards wound healing and reduction of uterine size in post LSCS women. It is also safe for human consumptions