Mitochondrial genome instability: its potential role in biomarker discovery for brain tumorigenesis

Background: Mitochondria are major cellular sources of reactive oxygen species (ROS) generation which can induce mitochondrial DNA (mtDNA) damage and lead to carcinogenesis. MtDNA 4,977-bp deletion as well as alteration in mtDNA copy number have been implicated in various types of human cancers....

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Bibliographic Details
Main Author: Yusoff, Abdul Aziz Mohamed
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2017
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Online Access:http://eprints.usm.my/57035/1/DR%20ABDUL%20AZIZ%20MOHAMED%20YUSOFF-Eprints.pdf
http://eprints.usm.my/57035/
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