Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.

Trigger finger is a term for stenosing tenovaginitis affecting the excursion of the long flexor of the hand at the area of zone II of the digit. Steroid injection is one of the treatment option. Triamcinolone is the steroid mainly used for trigger finger treatment. Hydroc'ortisone is used o...

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Main Author: Radzeli, Mohd Ramli
Format: Thesis
Language:English
Published: 2011
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Online Access:http://eprints.usm.my/55144/1/DR%20PREMANANDA%20RAJA%20AL%20MURUGESU%20-%2024%20pages.pdf
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spelling my.usm.eprints.55144 http://eprints.usm.my/55144/ Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study. Radzeli, Mohd Ramli R Medicine (General) Trigger finger is a term for stenosing tenovaginitis affecting the excursion of the long flexor of the hand at the area of zone II of the digit. Steroid injection is one of the treatment option. Triamcinolone is the steroid mainly used for trigger finger treatment. Hydroc'ortisone is used only in paeditric trigger finger. Therefore result and outcome of hydrocortisone in treatment of adult trigger finger still not establish. PURPOSE: This study was designed to test the nu11 hypothesis that there is no difference in resolution of trigger finger in term of pain, tenderness and triggering/locking in 3 months after injection with triamcinolone, a depot form of potent steroid or hydrocortisone, a highly soluble form but less potent steroid. METHODS: Seventy patients were enrolled in a prospective randomized controlled study comparing triamcinolone and hydrocortisone injection for idiopathic trigger finger. They were randomized into two groups; triamcinolone group and hydrocortisone group. All patients required to answer DASH questionnaire, give VAS score and evaluated for triggering/locking and tenderness at A 1 pulley before injection, immediately after injection and 3 months after injection. Fifty-nine patients completed the 3 months follow-up (28 triamcinolone arm, 31 dexamethasone arm). Outcome measures included the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, presence/absence of triggering/locking finger, presence/absence of A1 puiiey tenderness and pains severity base on visual analog scale. A Chi-square test and student t-test were used to compare both groups. RESULTS: Immediately after injection, absence of triggering was documented in 24 of 34 patients (70.6%) in the triamcinolone group and in 28 of 36 patients (77.8%) in the hydrocortisone group. The rates of resolution of triggering 3 months after injection were 22 of 28 (78.6%) in the triamcinolone group and 26 of 31 (83.9%) in the hydrocortisone group. In term of tenderness of AI pulley, immediately after injection, absence of tenderness was documented in 26 of 34 patients (76.5%) in the triamcinolone group and in 28 of 36 patients (77 .8%) in the hydrocortisone group. The rates of resolution of tenderness 3 months after injection were 18 of 28 (64.3%) in the triamcinolone group and 22 of 31 (71 %) in the hydrocortisone group. There were no significant differences between Disabilities of the Arm, Shoulder, and Hand scores and Visual Analog Scale score for pain immediately after injection and the 3-month follow-up. After the close of the study, there was no complication in both treatment groups. CONCLUSIONS: There is no significant different in term of resolution of tenderness over AI pulley, resolution triggering/locking, pain and physical disabilities score improvement between the two types of steroid injection. 2011 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/55144/1/DR%20PREMANANDA%20RAJA%20AL%20MURUGESU%20-%2024%20pages.pdf Radzeli, Mohd Ramli (2011) Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study. Masters thesis, Pusat Pengajian Sains Perubatan.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Radzeli, Mohd Ramli
Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
description Trigger finger is a term for stenosing tenovaginitis affecting the excursion of the long flexor of the hand at the area of zone II of the digit. Steroid injection is one of the treatment option. Triamcinolone is the steroid mainly used for trigger finger treatment. Hydroc'ortisone is used only in paeditric trigger finger. Therefore result and outcome of hydrocortisone in treatment of adult trigger finger still not establish. PURPOSE: This study was designed to test the nu11 hypothesis that there is no difference in resolution of trigger finger in term of pain, tenderness and triggering/locking in 3 months after injection with triamcinolone, a depot form of potent steroid or hydrocortisone, a highly soluble form but less potent steroid. METHODS: Seventy patients were enrolled in a prospective randomized controlled study comparing triamcinolone and hydrocortisone injection for idiopathic trigger finger. They were randomized into two groups; triamcinolone group and hydrocortisone group. All patients required to answer DASH questionnaire, give VAS score and evaluated for triggering/locking and tenderness at A 1 pulley before injection, immediately after injection and 3 months after injection. Fifty-nine patients completed the 3 months follow-up (28 triamcinolone arm, 31 dexamethasone arm). Outcome measures included the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, presence/absence of triggering/locking finger, presence/absence of A1 puiiey tenderness and pains severity base on visual analog scale. A Chi-square test and student t-test were used to compare both groups. RESULTS: Immediately after injection, absence of triggering was documented in 24 of 34 patients (70.6%) in the triamcinolone group and in 28 of 36 patients (77.8%) in the hydrocortisone group. The rates of resolution of triggering 3 months after injection were 22 of 28 (78.6%) in the triamcinolone group and 26 of 31 (83.9%) in the hydrocortisone group. In term of tenderness of AI pulley, immediately after injection, absence of tenderness was documented in 26 of 34 patients (76.5%) in the triamcinolone group and in 28 of 36 patients (77 .8%) in the hydrocortisone group. The rates of resolution of tenderness 3 months after injection were 18 of 28 (64.3%) in the triamcinolone group and 22 of 31 (71 %) in the hydrocortisone group. There were no significant differences between Disabilities of the Arm, Shoulder, and Hand scores and Visual Analog Scale score for pain immediately after injection and the 3-month follow-up. After the close of the study, there was no complication in both treatment groups. CONCLUSIONS: There is no significant different in term of resolution of tenderness over AI pulley, resolution triggering/locking, pain and physical disabilities score improvement between the two types of steroid injection.
format Thesis
author Radzeli, Mohd Ramli
author_facet Radzeli, Mohd Ramli
author_sort Radzeli, Mohd Ramli
title Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
title_short Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
title_full Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
title_fullStr Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
title_full_unstemmed Comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
title_sort comparison between triamcinalone injection and hydrocortisone injection in treatment of trigger finger: a prospective singled- blinded randomized controlled study.
publishDate 2011
url http://eprints.usm.my/55144/1/DR%20PREMANANDA%20RAJA%20AL%20MURUGESU%20-%2024%20pages.pdf
http://eprints.usm.my/55144/
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score 13.160551