Cover Image

Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines

Hevea brasiliensis rubber latex dialysed C-serum supernatant (DCS) sub-fraction has been reported to possess potential anti-proliferation activities against specific human breast (MDA-MB-231) and liver (HepG2) cancer cell lines through autoschizis cell death pathway. Further investigations on DCS tr...

Full description

Saved in:
Bibliographic Details
Main Author: Yang, Kok Lee
Format: Thesis
Language:English
Published: 2021
Subjects:
QH1 Natural history (General - Including nature conservation, geographical distribution)
Online Access:http://eprints.usm.my/53332/1/YANG%20KOK%20LEE%20-%20TESIS.pdf%20cut.pdf
http://eprints.usm.my/53332/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.usm.eprints.53332
record_format eprints
spelling my.usm.eprints.53332 http://eprints.usm.my/53332/ Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines Yang, Kok Lee QH1 Natural history (General - Including nature conservation, geographical distribution) Hevea brasiliensis rubber latex dialysed C-serum supernatant (DCS) sub-fraction has been reported to possess potential anti-proliferation activities against specific human breast (MDA-MB-231) and liver (HepG2) cancer cell lines through autoschizis cell death pathway. Further investigations on DCS treatment (concentrations ranged between 0 to 100 μg/mL) on anti-proliferative effect in this study have shown that IC50 of DCS was at 8.81 μg/mL and 22.12 μg/mL for DBTRG (human brain glioblastoma) and MKN74 (human gastric tubular adenocarcinoma), respectively. Although DCS showed specificity in cancer cell lines based on cell viability assays, its genotoxicity effects are important in view of its employment in human subjects if it would be developed into an anti-cancer drug. 2021-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/53332/1/YANG%20KOK%20LEE%20-%20TESIS.pdf%20cut.pdf Yang, Kok Lee (2021) Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic QH1 Natural history (General - Including nature conservation, geographical distribution)
spellingShingle QH1 Natural history (General - Including nature conservation, geographical distribution)
Yang, Kok Lee
Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines
description Hevea brasiliensis rubber latex dialysed C-serum supernatant (DCS) sub-fraction has been reported to possess potential anti-proliferation activities against specific human breast (MDA-MB-231) and liver (HepG2) cancer cell lines through autoschizis cell death pathway. Further investigations on DCS treatment (concentrations ranged between 0 to 100 μg/mL) on anti-proliferative effect in this study have shown that IC50 of DCS was at 8.81 μg/mL and 22.12 μg/mL for DBTRG (human brain glioblastoma) and MKN74 (human gastric tubular adenocarcinoma), respectively. Although DCS showed specificity in cancer cell lines based on cell viability assays, its genotoxicity effects are important in view of its employment in human subjects if it would be developed into an anti-cancer drug.
format Thesis
author Yang, Kok Lee
author_facet Yang, Kok Lee
author_sort Yang, Kok Lee
title Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines
title_short Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines
title_full Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines
title_fullStr Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines
title_full_unstemmed Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines
title_sort single agent and synergistic activity of latex c-serum with led red light in cancer cell lines
publishDate 2021
url http://eprints.usm.my/53332/1/YANG%20KOK%20LEE%20-%20TESIS.pdf%20cut.pdf
http://eprints.usm.my/53332/
_version_ 1738511190135406592
score 13.201949

Similar Items