Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
Short Tandem Repeats (STRs) loci are characterized by high level of length polymorphism within and among populations. This polymorphism makes it becomes a blue print for forensic purposes. In this study, STR is applied for determining the allele's frequencies in Duson population in Sabah. Th...
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| Main Author: | |
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| Format: | Monograph |
| Language: | English |
| Published: |
PPSP, Universiti Sains Malaysia
2007
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| Subjects: | |
| Online Access: | http://eprints.usm.my/50213/1/MOHD%20YUSMAIDIE%20BIN%20AZIZ%20-%2024%20pages.pdf http://eprints.usm.my/50213/ |
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| Summary: | Short Tandem Repeats (STRs) loci are characterized by high level of length
polymorphism within and among populations. This polymorphism makes it becomes a
blue print for forensic purposes. In this study, STR is applied for determining the allele's
frequencies in Duson population in Sabah. This is done by using three different STR loci
F13AOI, FESFPS and vWA. About 100 buccal swab samples from Dusun population
were collected. Each sample was separated into different envelopes and sealed. Then
DNA was extracted from the samples using simple procedure describe by Promega
followed by STR typing on the three locus using multiplex kits. Allele frequencies were
calculated and statistical analysis was then carried out. Comparative studies were carried
out with referring to allele distribution from other populations. This study produces a
database for random Duson population and hopefully will help in human identification in
Malaysia. We also fid out that the genotype frequency distributions do not deviate from
Hardy-Weinberg expectations. |
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