Allele frequencies of STRs (F13A01, FESFPS and vWA) in random Chinese population of Malaysia
Biochemical and molecular genetic markers have played a vital role in forensic analysis of bio .. specimens and in kingships testing. However with the advent of DNA profiling technique positive identification has become a reality. The science of DNA profiling had revamped analytical procedures em...
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| Format: | Article |
| Language: | English |
| Published: |
Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia
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| Online Access: | http://eprints.usm.my/46735/1/PTA...Saravanakumar%20A%2CL%20Maniam...2004...-24%20pages.pdf http://eprints.usm.my/46735/ |
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| Summary: | Biochemical and molecular genetic markers have played a vital role in forensic
analysis of bio .. specimens and in kingships testing. However with the advent of DNA
profiling technique positive identification has become a reality. The science of DNA
profiling had revamped analytical procedures employed in the analysis. Short Tandem
Repeats (STRs) DNA profiling is widely used in most of the laboratories for personal
identification. A population database on the STR to be employed for analysis is a
prerequisite. In the present study distribution of allele frequencies for three validated
STRs - F13A01, FESFPS, vWA was compiled for the ethnic Chinese population of
Malaysia. DNA samples form 100 random Chinese individual were processed using
multiplex primer mix. There is no significant deviation from the Hardy-Weinberg
equilibrium. The discrimination power of the three STRs is 0.9987. |
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