Immunohistochemical study of breast cancer antigens (part 1)
Survivin has been characterized as a member of the family of inhibitor of apoptosis proteins (lAP). It is a 16.5 kD protein made up of 142 amino acids. Survivin is expressed in the G2/M phase of the cell cycle. It has been previously sho\vn to be expressed in a large number of cancers, and its ex...
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Format: | Article |
Language: | English |
Published: |
Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia
2004
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Online Access: | http://eprints.usm.my/45612/1/GP...Immunohistochemical%20Study%20Of%20Breast%20Cancer%20Antihens%20%28Part%201%29...2004...-OCR.pdf http://eprints.usm.my/45612/ |
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Summary: | Survivin has been characterized as a member of the family of inhibitor of
apoptosis proteins (lAP). It is a 16.5 kD protein made up of 142 amino acids. Survivin is
expressed in the G2/M phase of the cell cycle. It has been previously sho\vn to be
expressed in a large number of cancers, and its expression has been associated with the
aggression of tumors, or with the poor survival of cancer patients. |
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