Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar

Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compou...

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Main Author: Md Yusoff, Nor Adlin
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf
http://eprints.usm.my/45446/
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spelling my.usm.eprints.45446 http://eprints.usm.my/45446/ Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar Md Yusoff, Nor Adlin RS1-441 Pharmacy and materia medica Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compounds in NPV based on polarity into an ethyl acetate extract (EE) and an aqueous extract (AE). AE was further fractionated using acid hydrolysis into two sub-fractions: SFI and SFII. NPV, EE, AE, SFI and SFII were administered using oral gavage in non diabetic and/or diabetic rats induced by streptozotocin (STZ). Blood glucose levels (BGLs), insulin levels, and liver and pancreatic histological changes were recorded. 2017-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf Md Yusoff, Nor Adlin (2017) Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Md Yusoff, Nor Adlin
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
description Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compounds in NPV based on polarity into an ethyl acetate extract (EE) and an aqueous extract (AE). AE was further fractionated using acid hydrolysis into two sub-fractions: SFI and SFII. NPV, EE, AE, SFI and SFII were administered using oral gavage in non diabetic and/or diabetic rats induced by streptozotocin (STZ). Blood glucose levels (BGLs), insulin levels, and liver and pancreatic histological changes were recorded.
format Thesis
author Md Yusoff, Nor Adlin
author_facet Md Yusoff, Nor Adlin
author_sort Md Yusoff, Nor Adlin
title Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_short Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_full Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_fullStr Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_full_unstemmed Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_sort antidiabetic activity of nypa fruticans wurmb. vinegar
publishDate 2017
url http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf
http://eprints.usm.my/45446/
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score 13.19449