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Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis

Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high speci...

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Main Author: Bukari, Bakhtiar Affendi
Format: Thesis
Language:English
Published: 2017
Subjects:
R735-854 Medical education. Medical schools. Research
Online Access:http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf
http://eprints.usm.my/45354/
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spelling my.usm.eprints.45354 http://eprints.usm.my/45354/ Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis Bukari, Bakhtiar Affendi R735-854 Medical education. Medical schools. Research Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis. 2017-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf Bukari, Bakhtiar Affendi (2017) Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R735-854 Medical education. Medical schools. Research
spellingShingle R735-854 Medical education. Medical schools. Research
Bukari, Bakhtiar Affendi
Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
description Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis.
format Thesis
author Bukari, Bakhtiar Affendi
author_facet Bukari, Bakhtiar Affendi
author_sort Bukari, Bakhtiar Affendi
title Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_short Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_full Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_fullStr Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_full_unstemmed Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_sort generation and characterisation of rna aptamers against esat6 protein from mycobacterium tuberculosis
publishDate 2017
url http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf
http://eprints.usm.my/45354/
_version_ 1646011328341475328
score 13.159267

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