Generation And Characterization Of Rna Aptamer Against rHuEPO-a By Selex Technology

• Main Author: Marimuthu, Citartan
• Format: Thesis
• Language: English
• Published: 2014
• Subjects: R735-854 Medical education. Medical schools. Research
• Online Access: http://eprints.usm.my/44994/1/CITARTAN%20MARIMUTHU.pdf; http://eprints.usm.my/44994/

Systematic Evolution of Ligands by Exponential Enrichment (SELEX) enables the isolation of aptamer (ssDNA or RNA that possesses high binding affinity and specificity against virtually any target molecules). In this study, a RNA aptamer against recombinant human EPO-alpha (rHuEPO-α) was successfully...