Agomelatine in Depressive Disorders: Its Novel Mechanisms of Action

• Main Authors: Srinivasan, Venkataramanujan, Zakaria, Rahimah, Othman, Zahiruddin, Lauterbach, Edward C., Acuña-Castroviejo, Darío
• Format: Article
• Language: English
• Published: American Psychiatric Publishing 2012
• Subjects: RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
• Online Access: http://eprints.usm.my/44437/1/2012_JNCN_-_Agomelatine_in_Depressive_Disorders.pdf; http://eprints.usm.my/44437/; https://neuro.psychiatryonline.org/doi/10.1176/appi.neuropsych.11090216

Disruptions in sleep and sleep–wake cycle regulation have been identified as one of the main causes for the pathophysiology of depressive disorders. The search has been on for the identification of an ideal antidepressant that could improve both sleep disturbances and depressive symptomatology...