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Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation

Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with...

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Main Author: Karim, Sabiha
Format: Thesis
Language:English
Published: 2011
Subjects:
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf
http://eprints.usm.my/42494/
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spelling my.usm.eprints.42494 http://eprints.usm.my/42494/ Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation Karim, Sabiha RS1-441 Pharmacy and materia medica Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with extrusion-spheronisation process in terms of physical characteristics and in-vitro dissolution profile of the developed formulations. The fast release paracetamol pellets were comprised of, microcrystalline cellulose, lactose, crospovidone and polyvinyl pyrrolidone-K90. 2011-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf Karim, Sabiha (2011) Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Karim, Sabiha
Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
description Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with extrusion-spheronisation process in terms of physical characteristics and in-vitro dissolution profile of the developed formulations. The fast release paracetamol pellets were comprised of, microcrystalline cellulose, lactose, crospovidone and polyvinyl pyrrolidone-K90.
format Thesis
author Karim, Sabiha
author_facet Karim, Sabiha
author_sort Karim, Sabiha
title Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_short Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_full Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_fullStr Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_full_unstemmed Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_sort design and evaluation of multiparticulate systems prepared using sieving-spheronisation and extrusionspheronisation
publishDate 2011
url http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf
http://eprints.usm.my/42494/
_version_ 1643710513758076928
score 13.214268

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