Biosynthetic production of human growth hormone gene in methylotrophic yeast, Pichia pastoris

• Main Authors: Loh, Danley, Muhammad, Tengku Sifzizul Tengku, Najimudin, Nazalan, Arip, Yahya Mat, Samian, Mohd Razip
• Other Authors: Ahmad, Abdul Latif
• Format: Book Section
• Language: English
• Published: Penerbit Universiti Sains Malaysia 2004
• Subjects: Q179.9-180 Research
• Online Access: http://eprints.usm.my/42453/1/pBIO21.pdf; http://eprints.usm.my/42453/

Human growth hormone (hGH) is secreted from the anterior pituitary gland and exerts a wide variety of functions such as, IGF-1 production, protein synthesis, glucose metabolism, lipolysis, lipogenesis, and cell proliferation/differentiation (Isaksson et al., 1985; Press, 1988; Thorner and Vance, 19...