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Syntheses And Antibacterial Screening Of Juglone Derivatives

The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-...

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Main Author: Tan , Daniel Teoh Chuan
Format: Thesis
Language:English
Published: 2010
Subjects:
QD1-65 General Including alchemy
Online Access:http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf
http://eprints.usm.my/41745/
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spelling my.usm.eprints.41745 http://eprints.usm.my/41745/ Syntheses And Antibacterial Screening Of Juglone Derivatives Tan , Daniel Teoh Chuan QD1-65 General Including alchemy The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-8-hydroxy-3-methylbenz[a] anthracene-7,12-dione (19) was synthesised from juglone in two steps. The first step was the Diels-Alder reaction and the second step was the aromatisation reaction. In addition, a new para-nitrojuglone derivative (51) was obtained as the sole isomeric product from the direct nitration of juglone. 2010-11 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf Tan , Daniel Teoh Chuan (2010) Syntheses And Antibacterial Screening Of Juglone Derivatives. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic QD1-65 General Including alchemy
spellingShingle QD1-65 General Including alchemy
Tan , Daniel Teoh Chuan
Syntheses And Antibacterial Screening Of Juglone Derivatives
description The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-8-hydroxy-3-methylbenz[a] anthracene-7,12-dione (19) was synthesised from juglone in two steps. The first step was the Diels-Alder reaction and the second step was the aromatisation reaction. In addition, a new para-nitrojuglone derivative (51) was obtained as the sole isomeric product from the direct nitration of juglone.
format Thesis
author Tan , Daniel Teoh Chuan
author_facet Tan , Daniel Teoh Chuan
author_sort Tan , Daniel Teoh Chuan
title Syntheses And Antibacterial Screening Of Juglone Derivatives
title_short Syntheses And Antibacterial Screening Of Juglone Derivatives
title_full Syntheses And Antibacterial Screening Of Juglone Derivatives
title_fullStr Syntheses And Antibacterial Screening Of Juglone Derivatives
title_full_unstemmed Syntheses And Antibacterial Screening Of Juglone Derivatives
title_sort syntheses and antibacterial screening of juglone derivatives
publishDate 2010
url http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf
http://eprints.usm.my/41745/
_version_ 1643710309611864064
score 13.188404

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