Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients
Aims: Health-Related Quality of Life (HRQoL) has been increasing attention in health outcome studies. Factors that individually influence HRQoL, diabetes self-care behaviors, and medication adherence have been widely investigated; however, most previous studies have not tested an integrated associ...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Elsevier
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/39048/ http://www.jctejournal.com/article/S2214-6237(17)30010-8/fulltext |
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| Summary: | Aims: Health-Related Quality of Life (HRQoL) has been increasing attention in health outcome studies.
Factors that individually influence HRQoL, diabetes self-care behaviors, and medication adherence have
been widely investigated; however, most previous studies have not tested an integrated association
between multiple health outcomes. The purpose of this study was to formulate a hypothetical structural
equation model linking HRQoL, diabetes distress, diabetes self-care activities, medication adherence and
diabetes-dependent QoL in patients with Type 2 Diabetes Mellitus (T2DM).
Methods: A cross-sectional study design was employed, and 497 patients with T2DM were recruited from
outpatient clinics in three public hospitals and one government clinic. The patients completed a series of
questionnaires. The hypothetical model was tested using Structural Equation Modeling (SEM) analysis.
Results: The values of the multiple fit indices indicated that the proposed model provided a good fit to the
data. SEM results showed that medication adherence (MMAS) had a significant direct effect on diabetes
distress (PAID) (Beta = �0.20). The self-care activities (SDSCA) construct was significantly related to PAID
(Beta = �0.24). SDSCA was found to have a significant relationship with HRQoL (SF-36) (Beta = 0.11).
Additionally, diabetes distress had a significant effect (Beta = �0.11) on HRQoL of patients. Finally,
ADDQoL had a significant effect on HRQoL (Beta = 0.12).
Conclusions: The various health outcome indicators such as self-care behaviors, diabetes distress, medication
adherence and diabetes-dependent QoL need to be considered in clinical practice for enhancing
HRQoL in those patients. |
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