Enhancement of BDNF Concentration and Restoration of the Hypothalamic-Pituitary-Adrenal Axis Accompany Reduced Depressive-Like Behaviour in Stressed Ovariectomised Rats Treated with Either Tualang Honey or Estrogen

• Main Authors: Al-Rahbi, Badriya, Zakaria, Rahimah, Othman, Zahiruddin, Hassan, Asma’, Ahmad, Asma Hayati
• Format: Article
• Language: English
• Published: Hindawi Publishing Corporation 2014
• Subjects: QM Human anatomy; QP1-(981) Physiology
• Online Access: http://eprints.usm.my/38971/1/Enhancement_of_BDNF_Concentration_and_Restoration_of_the_Hypothalamic-Pituitary-.pdf; http://eprints.usm.my/38971/; http://dx.doi.org/10.1155/2014/310821

A possible interaction between glucocorticoids and estrogen-induced increases in brain-derived-neurotrophic factor (BDNF) expression in enhancing depressive-like behaviour has been documented. Here we evaluated the effects of Tualang honey, a phytoestrogen, and 17