Construction and Evaluation of V. cholerae O139 Mutant, VCUSM21P, as a Safe Live Attenuated Cholera Vaccine

• Main Authors: Murugaiah, Chandrika, Nik Mohd Noor, Nik Zuraina, Mustafa, Shyamoli, Manickam, Ravichandran, Pattabhiraman, Lalitha
• Format: Article
• Language: English
• Published: Public Library of Science (PLoS) 2014
• Subjects: QR1-502 Microbiology
• Online Access: http://eprints.usm.my/38491/1/Construction_and_Evaluation_of_V._cholerae_O139_Mutant%2C.pdf; http://eprints.usm.my/38491/; https://doi.org/10.1371/journal.pone.0081817

Cholera is a major infectious disease, affecting millions of lives annually. In endemic areas, implementation of vaccination strategy against cholera is vital. As the use of safer live vaccine that can induce protective immunity against Vibrio cholerae O139 infection is a promising approach for im...