Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children

Suntu penelitian untuk mengetahui sensitivitas dan spesifisitas uji Typhidot dan Typhidot-M daLam mendiagnosis demam enterik pada anak-anak Malaysia telah dilakukan. Pasien dibagi dalam dua kelompok: (i) pasien dengan biakan darah dan-/ ataufeses positif S. typhi dan/atau dengan gambaran klinis yang...

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Main Authors: Choo, K.E., Davis, T.M.E., Ismail, A., Tuan Ismail, T.A., Ghazali, W.N.W.
Format: Article
Language:English
Published: Universitas Indonesia, Fakultas Kedokteran 1998
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Online Access:http://eprints.usm.my/38470/1/Comparative_sensitivity_and_specificity_of_Typhidot_and_Typhidot-M.pdf
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http://mji.ui.ac.id/journal/index.php/mji/article/view/1142/1044
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spelling my.usm.eprints.38470 http://eprints.usm.my/38470/ Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children Choo, K.E. Davis, T.M.E. Ismail, A. Tuan Ismail, T.A. Ghazali, W.N.W. QR1-502 Microbiology Suntu penelitian untuk mengetahui sensitivitas dan spesifisitas uji Typhidot dan Typhidot-M daLam mendiagnosis demam enterik pada anak-anak Malaysia telah dilakukan. Pasien dibagi dalam dua kelompok: (i) pasien dengan biakan darah dan-/ ataufeses positif S. typhi dan/atau dengan gambaran klinis yang jelas untuk demam enterik; (ii) pasien dengan kedua biakan negatif dan dengan gambaran klinis atau bukti lain adanya demam oleh sebab lain. Hasilnya menunjukkan bahwa Typhidot maupun TyphidorM sama sensitifnya dengan uji Widal. Uji Typhidot-M memiliki spesifisins yang sedikit Lebih tinggi daripada uji Typhido4 keduanya memiliki spesifisitas sekitar l0% Iebih baik daripada uji Widal. Data juga menunjukkan bahwa uji Typhidot-M mungkin dapat meningkntkan ketepatan diagnosis demam oleh sebab lain pada anak-anak, yang dibuktikan dengan perbaikan spesifitas. Baik uji Typhidot maupun Typhidot-M adalah alat bantu diagnosis yang cepat dan dapat diandalkan dalam penatalaksanaan demam enterik. Uji Typhidot-M mungkin lebih disukai daripada uji Typhidot dalam mengidentifikasi pasien yang menderita demam oleh sebab lain sementara ia daLam masa penyembuhan demam enterik. A study was carcied out to compare the sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of enteric fever in Malaysian children. The patients were divided into two groups: (i) those who were bLood and /or stool culture positive for S. typhi and/or who had clinical features strongly suggestive of enteric fever; (ii) those who were both culture - negative and had clinical or other evidence of another febrile illness. The results showed both Typhidot and Typhidot-M tests.were as sensitive as WidaL test. The Typhidot-M test hnd slightly greater specificity than the Typhidot test; both had around l07a better specificity than the Widal test. The data aLso suggest that the Typhidot-M test may, as evidenced by improved specificity, increase diagnostic accuracy for other febrile iLlnesses in children. The Typhidot and Typhidot-M are both prompt and reliable diagnostic aids in the management of enteric fever The typhidot-M test may be more preferable to the orginal Typhidot test in identifiing patients who develop other febrile illnesses whilst recovering from enteric fever. Universitas Indonesia, Fakultas Kedokteran 1998 Article PeerReviewed application/pdf en http://eprints.usm.my/38470/1/Comparative_sensitivity_and_specificity_of_Typhidot_and_Typhidot-M.pdf Choo, K.E. and Davis, T.M.E. and Ismail, A. and Tuan Ismail, T.A. and Ghazali, W.N.W. (1998) Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children. Medical Journal of Indonesia, 7 (20). pp. 284-285. ISSN 2252-8083 http://mji.ui.ac.id/journal/index.php/mji/article/view/1142/1044
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic QR1-502 Microbiology
spellingShingle QR1-502 Microbiology
Choo, K.E.
Davis, T.M.E.
Ismail, A.
Tuan Ismail, T.A.
Ghazali, W.N.W.
Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children
description Suntu penelitian untuk mengetahui sensitivitas dan spesifisitas uji Typhidot dan Typhidot-M daLam mendiagnosis demam enterik pada anak-anak Malaysia telah dilakukan. Pasien dibagi dalam dua kelompok: (i) pasien dengan biakan darah dan-/ ataufeses positif S. typhi dan/atau dengan gambaran klinis yang jelas untuk demam enterik; (ii) pasien dengan kedua biakan negatif dan dengan gambaran klinis atau bukti lain adanya demam oleh sebab lain. Hasilnya menunjukkan bahwa Typhidot maupun TyphidorM sama sensitifnya dengan uji Widal. Uji Typhidot-M memiliki spesifisins yang sedikit Lebih tinggi daripada uji Typhido4 keduanya memiliki spesifisitas sekitar l0% Iebih baik daripada uji Widal. Data juga menunjukkan bahwa uji Typhidot-M mungkin dapat meningkntkan ketepatan diagnosis demam oleh sebab lain pada anak-anak, yang dibuktikan dengan perbaikan spesifitas. Baik uji Typhidot maupun Typhidot-M adalah alat bantu diagnosis yang cepat dan dapat diandalkan dalam penatalaksanaan demam enterik. Uji Typhidot-M mungkin lebih disukai daripada uji Typhidot dalam mengidentifikasi pasien yang menderita demam oleh sebab lain sementara ia daLam masa penyembuhan demam enterik. A study was carcied out to compare the sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of enteric fever in Malaysian children. The patients were divided into two groups: (i) those who were bLood and /or stool culture positive for S. typhi and/or who had clinical features strongly suggestive of enteric fever; (ii) those who were both culture - negative and had clinical or other evidence of another febrile illness. The results showed both Typhidot and Typhidot-M tests.were as sensitive as WidaL test. The Typhidot-M test hnd slightly greater specificity than the Typhidot test; both had around l07a better specificity than the Widal test. The data aLso suggest that the Typhidot-M test may, as evidenced by improved specificity, increase diagnostic accuracy for other febrile iLlnesses in children. The Typhidot and Typhidot-M are both prompt and reliable diagnostic aids in the management of enteric fever The typhidot-M test may be more preferable to the orginal Typhidot test in identifiing patients who develop other febrile illnesses whilst recovering from enteric fever.
format Article
author Choo, K.E.
Davis, T.M.E.
Ismail, A.
Tuan Ismail, T.A.
Ghazali, W.N.W.
author_facet Choo, K.E.
Davis, T.M.E.
Ismail, A.
Tuan Ismail, T.A.
Ghazali, W.N.W.
author_sort Choo, K.E.
title Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children
title_short Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children
title_full Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children
title_fullStr Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children
title_full_unstemmed Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of Enteric fever in Malaysian children
title_sort comparative sensitivity and specificity of typhidot and typhidot-m tests in the diagnosis of enteric fever in malaysian children
publisher Universitas Indonesia, Fakultas Kedokteran
publishDate 1998
url http://eprints.usm.my/38470/1/Comparative_sensitivity_and_specificity_of_Typhidot_and_Typhidot-M.pdf
http://eprints.usm.my/38470/
http://mji.ui.ac.id/journal/index.php/mji/article/view/1142/1044
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score 13.160551