Molecular Dynamics Studies Of The Effects Of Neuraminidase Mutation On Oseltamivir Resistance

Peningkatan laporan mengenai virus influenza yang resistan terhadap oseltamivir (OTV) (contohnya mutasi H274Y pada neuraminidase, NA) telah menarik banyak perhatian para penyelidik. Banyak kajian telah dilakukan untuk memahami mekanisme rintangan OTV pada NA H274Y. The increased number of repo...

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Bibliographic Details
Main Author: Muhammad Yusuf, Muhammad Yusuf
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://eprints.usm.my/31515/1/THESIS_-_MUHAMMAD_YUSUF.pdf
http://eprints.usm.my/31515/
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Summary:Peningkatan laporan mengenai virus influenza yang resistan terhadap oseltamivir (OTV) (contohnya mutasi H274Y pada neuraminidase, NA) telah menarik banyak perhatian para penyelidik. Banyak kajian telah dilakukan untuk memahami mekanisme rintangan OTV pada NA H274Y. The increased number of reports on oseltamivir (OTV) resistant strains of influenza virus (e.g. H274Y mutation on its neuraminidase, NA) has created some causes for concern. Many studies have been conducted to uncover the mechanism of OTV resistances in H274Y NA.