Design, Synthesis and Molecular Docking Studies of Some Novel Spiro Derivatives By 1,3-Cycloaddition Reaction

• Main Authors: Hasmaruddin, Nurul Syazana, Osman , Hasnah, Mohamed Yusoff, Nadia, Ali, Mohamed Ashraf Ali, Hassan, Mohd. Zaheen
• Format: Conference or Workshop Item
• Language: English
• Published: 2016
• Subjects: QD1-999 Chemistry; QD241-441 Organic chemistry
• Online Access: http://eprints.usm.my/31335/1/Poster_SYAZANA.pdf; http://eprints.usm.my/31335/; http://icnp2016.umt.edu.my/wp-content/uploads/sites/70/2015/11/ICNP-2016-SCHEDULE.pdf

Synthesis of polycyclic compounds having spiro nucleus has attracted the attention of synthetic organic chemists because of their highly pronounced biological activities such as antiviral, antimicrobial etc. Therefore, the development of new, rapid, and clean synthetic routes of such compounds is o...