Serological Evidence Of Dengue Infection In Nonhuman Primates In Peninsular Malaysia

• Main Author: Kee , William Stuebing
• Format: Thesis
• Language: English
• Published: 2015
• Subjects: QH1 Natural history (General - Including nature conservation, geographical distribution)
• Online Access: http://eprints.usm.my/30403/1/William_Stuebing_USM_MSc_Thesis.pdf; http://eprints.usm.my/30403/

Jangkitan Virus Denggi (DENV) berlaku di kalangan manusia dan di dalam kitaran Silvatik. Pada tahun 2008 seorang pelajar universiti didiagnoskan dengan Demam Hemorajik Denggi (DHF) selepas ia mengembara di Semenanjung Malaysia dan pemencilan darah selanjutnya menunjukkan bahawa jangkitan itu adalah Serotip-2 DENV Silvatik. Kawasan Malaysia dengan kepadatan populasi yang tinggi didapati tidak mempunyai sebarang maklumat semasa berkenaan dengan kitaran DENV Silvatik. Dengue viruses (DENV) circulate in both human and sylvatic cycles. In 2008, a Malaysian university student was diagnosed with dengue hemorrhagic fever (DHF) and a sylvatic DENV serotype 2 was isolated from his blood. Current information on sylvatic DENV cycles in these heavily populated areas of Malaysia is nonexistent. Sylvatic DENV can cause severe disease (DHF) in humans. Therefore, the objective of this study was to determine the location and host species of sylvatic DENV cycles as a first step in assessing the risk that such zoonotic viruses pose to the surrounding human population