Porphyromonas gingivalis peptidylarginine deiminase substrate specificity

• Main Authors: Elizabeth-Anne, Farmer, Richard, Logan, Neville, Gully, Syatirah-Najmi, Abdullah, Llewellyn, Spargo
• Format: Article
• Language: English
• Published: Elsevier Sci Ltd 2015
• Subjects: Citrullination; Porphyromonas Gingivalis; Peptidylarginine Deiminase; Periodontitis; Rheumatoid Arthritis
• Online Access: http://ddms.usim.edu.my/handle/123456789/8366

Gram negative anaerobe Porphyromonas gingivalis is most commonly reported to be associated with severe forms of the disease. Although a variety of human tissues can produce a number of peptidylarginine deiminase (PAD), enzymes that convert peptide bound arginine residues to citrulline, P. gingivalis...