Palm tocotrienols decrease levels of pro-angiogenic markers in human umbilical vein endothelial cells (HUVEC) and murine mammary cancer cells

• Main Authors: Kanga Rani, Selvaduray,, Kalanithi, Nesaretnam,, Ammu K., Radhakrishnan,, Methil Kannan, Kutty,
• Format: Article
• Language: English
• Published: Springer 2015
• Subjects: Angiogenesis; Palm Tocotrienol; IL-6; IL-8; VEGF; VEGF Receptors
• Online Access: http://ddms.usim.edu.my/handle/123456789/8338

Anti-angiogenic therapy is widely being used to halt tumour angiogenesis. In this study, the anti-angiogenic activity of palm tocotrienol-rich fraction (TRF) and its individual components (gamma- and delta-tocotrienol) were first investigated in vitro in human umbilical vein endothelial cells (HUVEC...