Human mesenchymal stromal cells could deliver erythropoietin and migrate to the basal layer of hair shaft when subcutaneously implanted in a murine model

• Main Authors: P. L., Mok,, S. K., Cheong,, O., Ainoon,, K. H., Chua,, CF, Leong,
• Format: Article
• Language: English
• Published: Churchill Livingstone 2015
• Subjects: Hair Regeneration; Mesenchymal Stromal Cells; Nucleofection; MIDGE; Erythropoietin; Hemoglobin
• Online Access: http://ddms.usim.edu.my/handle/123456789/8285

Mesenchymal stromal cells (MSC) are an attractive cell-targeting vehicle for gene delivery. MIDGE (an acronym for Minimalistic, Immunologically Defined Gene Expression) construct is relatively safer than the viral or plasmid expression system as the detrimental eukaryotic and prokaryotic gene and se...