A single inhibitory upstream open reading frame (uORF) is sufficient to regulate Candida albicans GCN4 translation in response to amino acid starvation conditions
Candida albicans is a major fungal pathogen that responds to various environmental cues as part of its infection mechanism. We show here that the expression of C. albicans GCN4, which encodes a transcription factor that regulates morphogenetic and metabolic responses, is translationally regulated in...
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Main Authors: | Arunkumar, Sundaram,, Chris M., Grant, |
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Format: | Article |
Language: | English |
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Cold Spring Harbor Lab Press, Publications Dept
2015
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