A New Approach of Synthesizing Ferulate Ester, a Sunscreen Agent Via Lipase-Catalyzed Reaction
A new approach of synthesizing ferulate ester, a sunscreen agent was successfully developed via lipase-catalyzed reaction. Ferulic acid, a naturally occurring compound in plant was found to act as UV-absorber which can be applied in the cosmetic product. However, a low solubility in both aqueous...
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| Main Authors: | , , , |
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| Format: | Conference Paper |
| Language: | English |
| Published: |
2012
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| Subjects: | |
| Online Access: | http://ddms.usim.edu.my/handle/123456789/6108 |
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| Summary: | A new approach of synthesizing ferulate ester, a sunscreen agent was successfully
developed via lipase-catalyzed reaction. Ferulic acid, a naturally occurring compound in
plant was found to act as UV-absorber which can be applied in the cosmetic product.
However, a low solubility in both aqueous and organic phases has restricted its
application. Therefore, a study has to be embarked in order to modify their physical and
chemical properties by enzymatic synthesis. In this study, ferulate ester was synthesized
via two different stages are esterifition of ferulic acid with hexanol and transesterification
of hexyl ferulate with olive oil. As a preliminary study, only two parameters were chosen to
be optimized via conventional method of varying one parameter at-a-time approach. They
are effect of reaction time and reaction temperature. A study showed that the optimum
condition to produce ferulate ester was reaction time (RT); 8h and temperature (T); 60°C.
The product was then characterized for their chemical and physical properties such as
iodine value, saponification value and color analysis. Finally, the product was subjected to
analyze by using Fourier-transform infrared (RIR) spectrometer to determine the
presence of ester group in the product obtained. |
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