Haematologic profile of haemoglobin constant spring and its co-inheritance with alpha and beta thalassaemia among form four students in Negeri Sembilan

• Main Authors: Nahanthiran, Subithira, Nik Mustapha, Nik Hafidzah, Chellappah Thambiah, Subashini, Osman, Malina, Idris, Faridah, Md Noor, Sabariah
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/99293/1/2022121911433304_MJMHS_0734.pdf; http://psasir.upm.edu.my/id/eprint/99293/; https://medic.upm.edu.my/upload/dokumen/2022121911433304_MJMHS_0734.pdf

Introduction: In Malaysia, the commonest non-deletional alpha (α) thalassaemia is Haemoglobin Constant Spring (Hb CS) which occurs due to a mutation at the termination codon of α2 globin gene (TAA>CAA). Presence of an abnormal peak at Zone 2 on CE or presence of a small peak at c-window on HPLC c...