Aerosolized niosome formulation containing gemcitabine and cisplatin for lung cancer treatment: optimization, characterization and in vitro evaluation

• Main Authors: Mohamad Saimi, Norfatin Izzatie, Salim, Norazlinaliza, Ahmad, Noraini, Abdulmalek, Emilia, Abdul Rahman, Mohd Basyaruddin
• Format: Article
• Published: Multidisciplinary Digital Publishing Institute 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/95735/; https://www.mdpi.com/1999-4923/13/1/59

Gemcitabine (Gem) and cisplatin (Cis) are currently being used for lung cancer treatment, but they are highly toxic in high dosages. This research aimed to develop a niosome formulation containing a low-dosage Gem and Cis (NGC), as an alternative formulation for lung cancer treatment. NGC was prepar...