The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19

• Main Authors: Winarno, Didik Dwi, Tualeka, Abdul Rohim, Widajati, Noeroel, Jalaludin, Juliana, Huda, Nuh, Raden Khairiyatul Afiyah, Rahman, Firman Suryadi
• Format: Article
• Language: English
• Published: Institute of Medico-Legal Publications 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/95397/1/The%20effect%20of%20nitric%20oxide%20supplement%20intake%20on%20the%20value%20of%20hematological%20examination%20of%20health%20workers%20exposed%20to%20Covid-19.pdf; http://psasir.upm.edu.my/id/eprint/95397/; https://medicopublication.com/index.php/ijfmt/article/view/14706

Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chain reaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes, neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an important role in monitoring the course of covid-19 disease Macrophages release nitric oxide (NO) to kill parasites NO inhibits migration and adhesion of leucocytes to the endothelium. Metode: The research design used preexperimental with one group pre-post test, the total sample was 80 health workers who were exposed to Covid-19, the independent variable was the provision of NO and the dependent variable was the result of a hematological examination (leukocytes, lymposites, platelets, neutrophils, hemoglobin and NLR). The intervention was given NO 500 mg mixed with warm water 250 cc, given 3 times a day for 5 days, data analysis used the T-test with a significance value of a<0.05. Results: There is a difference in the results of the pre and post-test hematology giving NO to the results of the examination of leucocytes a=0.001, lymphocytes a=0.000, platelets a=0.000, neutrophils a=0.000, hemoglobin a=0.031, and NLR a=0.000. Conclusion: Giving NO to health workers exposed to Covid-19 can improve the hematology and immune systems to fight the corona virus.