Physicochemical characterization, cytotoxic effect and toxicity evaluation of Nanostructured Lipid Carrier loaded with Eucalyptol

• Main Authors: Mohd Izham, Mira Nadiah, Hussin, Yazmin, Che Rahim, Nurul Fattin, Aziz, Muhammad Nazirul Mubin, Yeap, Swee Keong, Rahman, Heshu Sulaiman, Masarudin, Mas Jaffri, Mohamad, Nurul Elyani, Abdullah, Rasedee, Mohammad Alitheen, Noorjahan Banu
• Format: Article
• Published: BioMed Central 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/94588/; https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-021-03422-y

Background: Eucalyptol is an active compound of eucalyptus essential oil and was reported to have many medical attributes including cytotoxic effect on breast cancer cells. However, it has low solubility in aqueous solutions which limits its bioavailability and cytotoxic efficiency. In this study,...