Naloxone-precipitated mitragynine withdrawal did not associate with increased anxiety-like behaviour in rats

• Main Authors: Harun, Norsyifa, Johari, Illa Syafiqah, Japarin, Rima Atria, Syuhadaa Bakar, Siti Najmi, Mat, Noorul Hamizah, Hassan, Zurina, Hassan, Haniza
• Format: Article
• Published: Malaysian Society for Biochemistry & Molecular Biology 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/94316/; https://msbmb2010.wixsite.com/mjbmb/april-2021

Kratom (Mitragyna speciosa Korth) is a plant species currently used as an alternative self-treatment for pain and management of opioid dependence and withdrawal. However, information on the effect of its negative emotional state of withdrawal, particularly of the main psychoactive constituent, mitra...