Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain

• Main Authors: Md Noh, Mohamad Syafeeq Faeez, Rajadurai, Naveen, Hassan, Thajunnisa, Alias, Mardziah, Robert, Penafort, Chong, Yip Boon
• Format: Article
• Published: Elsevier 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/93544/; https://www.sciencedirect.com/science/article/pii/S2214751921002425

Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present a young male presenting with acute back pain, initially suspicious of malignancy, with an eventual diagnosis of vertebral sarcoidosis; with sacrum, pelvic bone, and cutaneous involvement (Darier-Roussy disease), as well as associated mediastinal and abdominal lymphadenopathy. Following the diagnosis of vertebral sarcoidosis with associated Darier-Roussy disease, the patient was offered treatment but was not keen at the time of diagnosis. An outpatient appointment to re-discuss treatment options was given, should it be pursued. Conclusion: Vertebral sarcoidosis with associated Darier-Roussy disease is an extremely rare clinical entity, with multiple differential diagnoses. Pathological examination is confirmatory and should be pursued for accurate diagnosis and treatment.