Ultrasound-assisted extraction conditions optimisation using response surface methodology from Mitragyna speciosa (Korth.) Havil leaves

• Main Authors: Zakaria, Fazila, Tan, Jen Kit, Mohd Faudzi, Siti Munirah, Abdul Rahman, Mohd Basyaruddin, Ashari, Siti Efliza
• Format: Article
• Published: Elsevier 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/93460/; https://www.sciencedirect.com/science/article/pii/S135041772100393X

The optimisation of the Ultrasound-Assisted Extraction (UAE) method was investigated by employing the Central Composite Rotatable Design (CCRD) of Response Surface Methodology (RSM). The UAE method was based on a simple ultrasound treatment using methanol as the extraction medium to facilitate the c...