Iron chelation properties of green tea Epigallocatechin-3-Gallate (EGCG) in colorectal cancer cells: analysis on Tfr/Fth regulations and molecular docking

• Main Authors: Md Nesran, Zarith Nameyrra, Shafie, Nurul Husna, Md Tohid, Siti Farah, Norhaizan, Mohd Esa, Ismail, Amin
• Format: Article
• Language: English
• Published: Hindawi Publishing Corporation 2020
• Online Access: http://psasir.upm.edu.my/id/eprint/89467/1/TEA.pdf; http://psasir.upm.edu.my/id/eprint/89467/; https://www.hindawi.com/journals/ecam/2020/7958041/

In many studies, green tea epigallocatechin-3-gallate (EGCG) has already shown its therapeutic effects in colorectal cancer cells (CRC). However, its mechanism of actions in CRC is poorly elucidated. Hence, this study attempts to elucidate the mechanism of actions of green tea ECGG via iron chelatio...