Evaluation of the proper dosage of lapatinib and its safety in dogs

• Main Authors: Tanaka, Yuiko, Watanabe, Manabu, Saeki, Kohei, Ong, Siew Mei, Yoshitake, Ryohei, Imamura, Shohei, Nishimura, Ryohei, Sugano, Sumio, Nakagawa, Takayuki
• Format: Article
• Language: English
• Published: Tokyo Metropolitan Institute of Medical Science 2020
• Online Access: http://psasir.upm.edu.my/id/eprint/88878/1/DOG.pdf; http://psasir.upm.edu.my/id/eprint/88878/; https://www.jstage.jst.go.jp/article/trs/2/3/2_2020-013/_html/-char/en

Lapatinib is a low-molecular-weight agent targeting the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). It is one of the antitumor agents used against advanced breast cancer in human. We intended to apply it against canine mammary gland tumors (cMGTs). To...