Water-assisted synthesis of mesoporous calcium carbonate with a controlled specific surface area and its potential to ferulic acid release

• Main Authors: Kadota, Kazunori, Ibe, Toi, Sugawara, Yuto, Takano, Hitomi, Yusof, Yus Aniza, Uchiyama, Hiromasa, Tozuka, Yuichi, Yamanaka, Shinya
• Format: Article
• Published: Royal Society of Chemistry 2020
• Online Access: http://psasir.upm.edu.my/id/eprint/86510/; https://pubs.rsc.org/en/content/articlelanding/2020/ra/d0ra05542e

A carbonation process to control the specific surface area of mesoporous calcium carbonate and the dissolution profile of ferulic acid on mesoporous carbonate particles are presented. The effects of water content on the physicochemical properties, specific surface area, pore size, crystallinity, and morphology are evaluated. Mesoporous calcium carbonate particles are synthesised with well-controlled specific surface areas of 38.8 to 234 m2 g-1. Each of the submicron-size secondary particles consists of a primary particle of nano-size. During secondary particle formation, primary particle growth is curbed in the case with less water content. By contrast, growth is promoted via dissolution and recrystallisation in the presence of water. The release rates of ferulic acid are gradually enhanced with increasing specific surface area of the mesoporous calcium carbonate, that reflects crystallinity of ferulic acid.