Inoculation of fowlpox viruses coexpressing avian influenza H5 and chicken IL-15 cytokine gene stimulates diverse host immune responses

• Main Authors: Abdul Razak, Mariatulqabtiah, Nor Majid, Nadzreeq, Giotis, Efstathios S., Omar, Abdul Rahman, Skinner, Michael A.
• Format: Article
• Language: English
• Published: Malaysian Society for Molecular Biology and Biotechnology 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/80278/1/Inoculation%20of%20fowlpox%20viruses%20coexpressing%20avian%20influenza%20H5%20and%20chicken%20IL-15%20cytokine%20gene%20stimulates%20diverse%20host%20immune%20responses.pdf; http://psasir.upm.edu.my/id/eprint/80278/; https://www.researchgate.net/publication/331220747_Inoculation_of_fowlpox_viruses_coexpressing_avian_influenza_H5_and_chicken_IL-15_cytokine_gene_stimulates_diverse_host_immune_responses

Fowlpox virus (FWPV) has been used as a recombinant vaccine vector to express antigens from several important avian pathogens. Attempts have been made to improve vaccine strains induced-host immune responses by coexpressing cytokines. This study describes the construction of recombinant FWPV (rFWPV)...