Evaluation of in vitro release kinetics and mechanisms of curcumin-loaded cockle shell-derived calcium carbonate nanoparticles

• Main Authors: Mailafiya, Maryam Muhammad, Abubakar, Kabeer, Danmaigoro, Abubakar, Chiroma, Samaila Musa, Abdul Rahim, Ezamin, Mohd Moklas, Mohamad Aris, Abu Bakar @ Zakaria, Md Zuki
• Format: Article
• Published: BioMedPress 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/79756/; http://www.bmrat.org/index.php/BMRAT/article/view/580

Introduction: Curcumin has remarkable pharmacological activities but remains clinically constrained due to its poor bioavailability as a result of insolubility. This has necessitated the search for natural inorganic materials for curcumin delivery. Cockleshells are external hard materials of marine...