Analysis of MTHFR and MTRR gene polymorphisms in Iranian ventricular septal defect subjects

• Main Authors: Pishva, Seyyed Reza, Vasudevan, Ramachandran, Etemad, Ali, Heidari, Farzad, Komara, Makanko, Ismail, Patimah, Othman, Fauziah, Karimi, Abdollah, Sabri, Mohammad Reza
• Format: Article
• Language: English
• Published: MDPI 2013
• Online Access: http://psasir.upm.edu.my/id/eprint/78040/1/78040.pdf; http://psasir.upm.edu.my/id/eprint/78040/; https://www.mdpi.com/1422-0067/14/2/2739

Ventricular septal defect (VSD) is one of the most common types of congenital heart defects (CHD). There are vivid multifactorial causes for VSD in which both genetic and environmental risk factors are consequential in the development of CHD. Methionine synthase reductase (MTRR) and methylenetetrahy...