Zerumbone-loaded nanostructured lipid carrier induces apoptosis of canine mammary Adenocarcinoma cells

• Main Authors: Foong, Jia Ning, Selvarajah, Gayathri Thevi, Rasedee, Abdullah, Rahman, Heshu Sulaiman, Chee, Wun How, Chaw, Yee Beh, Teo, Guan Young, Chi, Ling Ku
• Format: Article
• Language: English
• Published: Hindawi 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/74464/1/ZERUM.pdf; http://psasir.upm.edu.my/id/eprint/74464/; https://www.hindawi.com/journals/bmri/2018/8691569/

Canine mammary gland tumor (CMT) is the most common tumor in intact female dog. Zerumbone (ZER) has promising anticancer properties, but plagued with poor water solubility, poor absorption, bioavailability, and delivery to target tissues. To solubilize, ZER was loaded into nanostructured lipid carri...