Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation

• Main Authors: Ng, Chin Theng, Fong, Lai Yen, Tan, Jun Jie, Rajab, Nor Fadilah, Abas, Faridah, Shaari, Khozirah, Chan, Kok Meng, Fariza Juliana, Yong, Yoke Keong
• Format: Article
• Language: English
• Published: BMC 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/74422/1/Water%20extract%20of%20Clinacanthus%20nutans%20leaves%20exhibits%20in%20vitro%2C%20ex%20vivo%20and%20in%20vivo%20anti-angiogenic%20activities%20in%20endothelial%20cell%20via%20suppression%20of%20cell%20proliferation.pdf; http://psasir.upm.edu.my/id/eprint/74422/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035421/

Background: Clinacanthus nutans (Burm. f.) Lindau. has traditionally been using in South East Asia countries to manage cancer. However, scientific evidence is generally lacking to support this traditional claim. This study aims to investigate the in vitro, ex-vivo and in vivo effects of C. nutans ex...