Targeting energy metabolism to eliminate cancer cells

• Main Authors: Shahruzaman, Shazwin Hani, Fakurazi, Sharida, Maniam, Sandra
• Format: Article
• Language: English
• Published: Dove Medical Press 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/74082/1/Targeting%20energy%20metabolism%20to%20eliminate%20cancer%20cells.pdf; http://psasir.upm.edu.my/id/eprint/74082/

Adaptive metabolic responses toward a low oxygen environment are essential to maintain rapid proliferation and are relevant for tumorigenesis. Reprogramming of core metabolism in tumors confers a selective growth advantage such as the ability to evade apoptosis and/or enhance cell proliferation and...