Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis

• Main Authors: Fuah, Kar Wah, Lim, Christopher Thiam Seong, Pang, Daniel C. L., Jin, Shyan Wong
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/73846/1/Selected%20organs%20of%20marine%20mussels%20as%20accurate%20biomonitors%20of%20metal%20bioavailability%20and%20contamination%20in%20the%20coastal%20waters%20challenges.pdf; http://psasir.upm.edu.my/id/eprint/73846/

Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property. In patients with renal impairment, even administering the usual recommended dose of TXA can induce...