Pre-emptive multimodal analgesia with tramadol and ketamine–lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy

• Main Authors: Kaka, Ubedullah, Rahman, Nor Alimah, Abubakar, Adamu Abdul, Goh, Yong Meng, Fakurazi, Sharida, Omar, Mohamed Ariff, Chen, Hui Cheng
• Format: Article
• Language: English
• Published: Dove Medical Press 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/73596/1/Pre-emptive%20multimodal%20analgesia%20with%20tramadol%20and%20ketamine%E2%80%93lidocaine%20infusion%20for%20suppression%20of%20central%20sensitization%20in%20a%20dog%20model%20of%20ovariohysterectomy.pdf; http://psasir.upm.edu.my/id/eprint/73596/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905489/pdf/jpr-11-743.pdf

Objectives: The effects of pre-emptive infusion of ketamine-lidocaine with tramadol on the suppression of central sensitization were investigated in a dog ovariohysterectomy model. Patients and methods: Twelve dogs were randomly assigned to two groups: ketamine-lidocaine-tramadol (KLT) and tramadol...