Potential ability of phytochemical in inhibition of invadopodia formation and HIF-1α in cancer metastasis

• Main Authors: Hamad, Hamad Ali, Gopalsamy, Banulata, Cheah, Yoke Kqueen, Md Hashim, Nur Fariesha
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/70050/1/2019070210030311_MJMHS_SP2_2019.pdf; http://psasir.upm.edu.my/id/eprint/70050/; https://medic.upm.edu.my/upload/dokumen/2019070210030311_MJMHS_SP2_2019.pdf

Cancer metastasis is a multistep process, which results in cancer cells disseminating to other organs. The crucial metastasis step involves cancer invasion which occurs via actin-protrusion by invasive malignant cells, termed as invadopodia. In solid tumours, invadopodia formation increases as a res...