Acute toxicity study of intravenous administration of thymoquinone-loaded nanostructured lipid carrier (TQ-NLC) in Sprague dawley rats

• Main Authors: Saiful Yazan, Latifah, Mohd Azlan, Siti Nabilahuda, Zakarial Ansar, Fatin Hannani, Gopalsamy, Banulata
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/70044/1/2019070210012408_MJMHS_SP2_2019.pdf; http://psasir.upm.edu.my/id/eprint/70044/; https://medic.upm.edu.my/upload/dokumen/2019070210012408_MJMHS_SP2_2019.pdf

Introduction: Thymoquinone (TQ), a bioactive compound from Nigella sativa is known for its various medicinal properties. Due to the low solubility of TQ, nanostructured lipid carrier (NLC) has been used as a delivery system to improve its efficacy. Nevertheless, the effect of TQ-NLC when administere...