Microarray-based genomic analysis identifies germline and somatic copy number variants and loss of heterozygosity in acute myeloid leukaemia

• Main Authors: Ambayya @ Ampiah, A Angeli, Sasmita, Andrew Octavian, Seman, Zainina, Chang, Kian Meng, Sathar, Jameela, Yegappan, Subramanian, Md Noor, Sabariah
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/66170/1/2018121312053102_MJMHS_December_2018.pdf; http://psasir.upm.edu.my/id/eprint/66170/; http://www.medic.upm.edu.my/upload/dokumen/2018121312053102_MJMHS_December_2018.pdf

Introduction: Insights into molecular karyotyping using comparative genomic hybridization (CGH) and single nucleotide polymorphism (SNP) arrays enable the identification of copy number variations (CNVs) at a higher resolution and facilitate the detection of copy neutral loss of heterozygosity (CN-LO...