Urinary metabolic profiling of cisplatin nephrotoxicity and nephroprotective effects of Orthosiphon stamineus leaves elucidated by 1H NMR spectroscopy

• Main Authors: Pariyani, Raghunath, Ismail, Intan Safinar, Azam, Amalina, Khatib, Alfi, Abas, Faridah, Shaari, Khozirah, Hamzah, Hazilawati
• Format: Article
• Language: English
• Published: Elsevier 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/63647/1/Urinary%20metabolic%20profiling%20of%20cisplatin%20nephrotoxicity%20and%20nephroprotective%20effects%20of%20Orthosiphon%20stamineus%20leaves%20elucidated%20by%201H%20NMR%20spectroscopy.pdf; http://psasir.upm.edu.my/id/eprint/63647/; https://www.sciencedirect.com/science/article/pii/S0731708516313292?via%3Dihub

Orthosiphon stamineus (OS) is a popular medicinal herb used in traditional Chinese medicine as a diuretic agent and for renal system disorders. This study employed 1H NMR based metabolomics approach to investigate the possible protective activity of OS in cisplatin induced nephrotoxicity owing to it...