Understanding the mode-of-action of Cassia auriculata via in silico and in vivo studies towards validating it as a long term therapy for type II diabetes

• Main Authors: Fauzi, Fazlin Mohd, John, Cini Mathew, Karunanidhi, Arunkumar, Mussa, Hamse Y., Ramasamy, Rajesh, Adam, Aishah, Bender, Andreas
• Format: Article
• Language: English
• Published: Elsevier 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/63629/1/Understanding%20the%20mode-of-action%20of%20Cassia%20auriculata%20via%20in%20silico%20and%20in%20vivo%20studies.pdf; http://psasir.upm.edu.my/id/eprint/63629/

Ethnopharmacological relevance: Cassia auriculata (CA) is used as an antidiabetic therapy in Ayurvedic and Siddha practice. This study aimed to understand the mode-of-action of CA via combined cheminformatics and in vivo biological analysis. In particular, the effect of 10 polyphenolic constituents...